What We Do
Featured Research Topic: Artificial Cells
The architecture of life is based on cells (microscale containers), which have organelles, i.e., smaller containers inside them. We are trying to mimic this by creating microscale capsules that have smaller capsules inside them. These multicompartment capsules (MCCs) can contain nanoparticles, enzymes, or bacteria in specific inner compartments (see paper in Chemical Science, 2017). We are collaborating with Prof. Bill Bentley (BioE) in this research.
Featured Application: Stopping Bleeding
Stopping blood loss from wounds is crucial during surgeries and on the battlefield. We got into this area when we discovered a ‘hemostatic’ polymer that is able to convert liquid blood into a gel (see above) by a self-assembly mechanism. The same polymer rapidly arrests bleeding from severe injuries in animal models. This technology won the Invention of the Year award at UMD in 2009, and since then has been patented and FDA-approved. Gel-e, Inc., a company run by a former student, is bringing this to the market.